Manuscript Submission Requirements Checklist

Correspondence should be addressed to the Editor-in-Chief at EIC@estlett.acs.org.


  • Cover letter
  • Title: Titles should be clear and concise; they must match between manuscript file and electronic submission.
  • Author list with affiliations: must match between electronic entry and manuscript file
  • Abstract
  • Keywords and Synopsis
  • Manuscript File: Clean with no highlighting or comments and all changes accepted.
  • (Highly encouraged) Have a colleague in another field read as test for accessibility.
  • Tables/Schemes/Figures: Text should be clear and legible, with fonts no smaller than 8 pt.
  • Figures: must be labeled sequentially and match numbered references in article (manuscript and Supporting Information). Where appropriate, label all subsections by letter.
  • Supporting Information (if any) must be included in the electronic submission.
  • Table of Contents Graphic (TOC Graphic)
  • References: no specific format is required, but it must be sufficient to aid referees in their reviewing duties

Scope of the Journal

Environmental Science & Technology Letters (ES&T Letters) is a cutting-edge journal for the rapid disclosure of urgent and impactful research results where immediate availability is of importance to the environmental science, engineering, and health community. It publishes papers that describe significant scientific advances or novel technologies in the broad field of environmental science and technology.  The journal invites brief communications (Letters) of experimental or theoretical results in all aspects of environmental science, both pure and applied. The journal also publishes Reviews, highlighting urgent, timely and new and emerging themes in environmental research that may not yet have an extensive literature base but are gathering momentum and warrant greater exposure with the identification of further research needs. Global Perspectives is a unique article type providing rapid exposure, insights, critiques, syntheses and recommendations on urgent, timely and new global strategic directions, topics and ambitions in environmental science and technology. Finally, Highlight is a new article type opportunity to publish a short opinion or news piece capturing information of pressing importance to the wider environmental science and technology community. For all article types, authors should provide enough background information to place their work in context and to justify the rapid publication format. The editors place strong emphasis on the urgency, originality, and quality of the work.


The scope of ES&T Letters is broad, covering all areas of environmental science and technology including characterization of natural and affected environments, environmental processes, fate, transport and transformation in natural and engineered systems, environmental measurement methods, environmental aspects of nanotechnology, novel remediation and control technology, biogeochemical cycling, ecotoxicology and human environmental health, sustainability and energy and the environment. ES&T Letters focuses particularly on the chemistry of processes in the environment, including those affected by human activities. This includes biological and physical phenomena that are specifically relevant to the understanding and management of the environment. ES&T Letters also publishes papers that describe significant scientific advances or novel technologies for remediation, control, and pollution prevention. The journal appeals to a multidisciplinary and diverse audience of scientists, policy makers and the broad environmental community.


Prospective authors are encouraged to review recent issues of ES&T Letters to gain an understanding of the topics that are of greatest interest to the journal’s readers, and they are expected to establish in their cover letters the relevance of their submissions to the community.


Note: Due to the volume of manuscripts received, ES&T Letters is unable to respond to pre-submission inquiries.

Thematic Section Headings

Current ES&T Letters topical categories are as follows:


  • Biogeochemical Cycling
  • Bioremediation and Biotechnology
  • Data Science
  • Ecotoxicology and Public Health
  • Energy and Climate
  • Occurrence, Fate, and Transport of Aquatic and Terrestrial Contaminants
  • Occurrence, Fate, and Behavior of Contaminants in Indoor Air and Atmosphere
  • Physico-Chemical Treatment and Resource Recovery
  • Sustainable Systems


These categories are periodically reviewed and may be changed.

Manuscript Types

ES&T Letters accepts the following manuscript types: Letters, Reviews, Global Perspectives, Highlight, and Correspondence/Rebuttals. A full description of each manuscript type is shown below:



The length of a Letter can be up to 3,000 word equivalents and this includes 200 words for each graphic element such as a table or figure. For example, a document with two figures and one table (for a total of 600 word equivalents) could have 2,400 written words in the manuscript and meet the 3,000 word equivalent requirement. The abstract, figure captions, TOC graphic, acknowledgments, and references are not included in the word count. Manuscripts should not contain large tables of data or more than a few plots or schematics in a single figure.


ES&T Letters Expectations

ES&T Letters strives to publish Letters reporting only original research of broad scientific significance and environmental importance that is expected to have a definable impact on the advancement of environmental chemistry, science, technology, health, and policy. Originality is defined as new experimental data, new interpretations of existing data, or new theoretical analyses of environmental phenomena. Significance will be judged with respect to the breadth of impact of the reported findings. Manuscripts that report data of a routine nature will not be accepted. For example, studies that describe only the outcomes of standard laboratory tests, or field tests of limited scope, are not appropriate. Letters must state the relevance of the research to natural and/or engineered environmental systems and technologies, and papers that fail to demonstrate their environmental relevance will be rejected without external review. For example, it is not sufficient that the paper describe work on a compound that may occur in the environment if the study does not provide information that is clearly related to that compound’s fate, transport, transformation, or effects in the environment. Manuscripts that emphasize analytical chemistry research must provide a meaningful yet concise argument that the method represents a significant advance in the environmental field. Manuscripts that do not include results from the application of the method either to real environmental samples or to samples that simulate environmental samples in a meaningful manner will be declined. Authors should show that a new analytical method has been thoroughly developed and its quality ensured.


Letters that describe advances in environmental technologies may include works on remediation and control processes and on new processes for sustainability. These manuscripts should include evaluations performed under environmentally realistic conditions. Letters that describe laboratory-scale studies should make meaningful and unbiased comparisons to existing approaches but should not make claims about the economics or relative advantages of the technology without pilot- or full-scale validation studies or properly validated models. Papers describing advances in treatment technologies for remediation of contaminated environments or control of emissions should go beyond kinetics and treatability studies by exploring the mechanisms of the technology or developing process models to describe the technique. Routine treatability studies will not be considered for publication. Papers in the area of ecotoxicology and human environmental health should provide novel information on effects of chemicals or lead to new insights into the mechanisms and processes underlying effects of chemicals and other stressors. ES&T Letters also encourages submission of studies that address challenges associated with the "Replacement, Reduction, and Refinement" of animal studies. At submission, authors must provide a short synopsis statement (approximately 20 words), placed after the abstract, stating the environmental relevance and significance of their research work. Authors are also expected to provide an explanation in their cover letter why they believe the manuscript belongs in ES&T Letters and why their research will interest our readers with an emphasis on the novelty and environmental relevance of the contribution.


ES&T Letters Minimum Requirements

  • All studies must clearly articulate the environmental relevance of the study to the broad ES&T Letters community.
  • Studies should provide novel insights into relevant environmental processes or mechanisms, i.e., studies that only describe the outcomes of standard laboratory or field tests or commercially available products are not appropriate for publication in ES&T Letters.
  • An assessment of uncertainty or sensitivity analysis should be included in reported data where applicable, with adequate quality assurance/quality control reported. New analytical methods should be thoroughly developed and quality ensured.
  • Manuscripts should include evaluations performed under environmentally realistic conditions and concentrations.  Concentrations and treatment levels should be reported as measured and not nominal.  Ensure that key variables are measured and reported if relevant (e.g., pH).
  • Manuscripts on toxicity and ecotoxicity should include positive and negative controls and consider multiple concentrations relevant to environmental exposures and/or a time-course study. Results should inform AOPs or mechanisms of action.
  • The scope of the reported data in ambient monitoring studies must yield conclusions applicable to more than the particular site or time when the data were taken, i.e., findings should not be location specific representing a case study, but rather generalizable and/or transferable to other contexts.
  • Studies on environmental contaminants should provide information that is clearly related to that compound’s fate, transport, transformation and/or effects in the environment.
  • Manuscripts on adsorption should consider kinetics as well as isotherms. First-principle models of mass transfer are preferred over purely empirical models.
  • Manuscripts that emphasize chemical engineering, new catalysts synthesis or analytical chemistry must provide a concise argument that the research represents an advance that is of primary importance to the environmental field and include comparison to state-of-the-art approaches where appropriate.
  • Manuscripts on novel materials (e.g., sorbents or catalysts) should demonstrate the materials have been tested under at least one environmental condition using relevant concentrations of target contaminant.
  • Manuscripts on air quality and particulate matter should include adequate characterization of the particles relevant to the study.
  • Articles describing advances in treatment technologies for remediation of contaminated environments or control of emissions should go beyond kinetics and treatability studies by exploring the mechanisms of the technology or develop process models to describe the technique.
  • If a manuscript proposes a new application, a general energy analysis or life-cycle assessment should be provided and compared against conventional methods.
  • Articles that describe laboratory-scale studies should make meaningful and unbiased comparisons to existing approaches but should not make claims about the economics or relative advantages of the technology without pilot- or full-scale validation studies or properly validated models.


Manuscripts that report on findings of a less urgent nature may be submitted to Environmental Science & Technology (ES&T) as a full research article.


Letters are reviewed initially by the Editor-in-Chief, then, if appropriate, by an assigned editor and then, if appropriate, by other scientists who assess the significance, originality, and validity of the work. The Editor-in-Chief and associate editors, listed in the ES&T Letters masthead, make final decisions about all research material published in ES&T Letters.



Reviews in ES&T Letters are unique as they are intended to highlight novel, emerging, forward-looking, pressing, often urgent and quickly developing areas of research, that are new and may not yet have an extensive literature base but are gathering momentum and warrant greater exposure and the consideration of forward research needs. Reviews should improve readers’ knowledge through discriminating comparisons and insightful organization of the material. Criteria for acceptability include the current importance of the field under review, the thoroughness of the literature coverage, clarity, and clear identification of research needs. Comprehensive reviews of more established areas are not appropriate (a Review submission in ES&T may be appropriate in this case).

Authors are also expected to provide an explanation in their cover letter why they believe the manuscript belongs in ES&T Letters and why their research will interest our readers with an emphasis on why this emerging area is in need of review (novelty and emerging/developing nature of the research) and environmental relevance of the contribution.

A brief methods section should present the review strategy including the search terms used when searching the literature, the databases in which the search was conducted, studies identified by other search methods, and a clear logic for inclusion and exclusion of articles in the review. Enough information should be provided that the search could be replicated if needed, and inclusion of documentation of the review approach and results in the Supporting Information is encouraged. Authors are also encouraged to identify the type of review they are submitting using an established review article typology framework (i.e., scoping review, systematic review, critical review, etc.)

Length Limit: The length of a Review is expected to be a maximum of 7500-word equivalents, but up to 10,000 words may be allowed at discretion of the handling editor. Word counts include 200 words for each graphic element such as a concise table or figure.  For example, three figures and two tables would count a total of 1000 words. The abstract, figure captions, TOC graphic, acknowledgments, and references are not included in the word count. Manuscripts should not contain large tables of data or more than a few plots or schematics in a single figure. Extensive tables should be placed in the Supporting Information.

At submission, authors must provide a short synopsis statement (approximately 20 words), placed after the abstract, stating the environmental relevance and significance of their work.


Global Perspectives

Global Perspectives (length limit: 3,000 to 5,000 word-equivalents) will provide rapid exposure, insights, critiques, syntheses and recommendations on urgent, timely and new global strategic directions, topics and ambitions in environmental science and technology.  Global perspective articles will highlight topics gathering global attention and funding.  These will be in response to emerging environmental challenges such as chemical and biological impacts of environmental concern, global population expansion, demands for clean water, and food and energy demand increases alongside a context of global climate change. Global Perspectives are peer-reviewed and may be invited or contributed without invitation.


Please note: Potential authors of Global Perspectives must first submit a proposal and cover letter (via the ES&T Letters submission site in the ACS Paragon Plus Environment). The proposal, to be uploaded as a single manuscript file, should include the following details:

  1. Proposed title
  2. Author names and affiliations
  3. Corresponding author’s email address, profile on institutional website (if available), and Google Scholar, Web of Science, or Scopus profile
  4. Abstract (length limit: 500 words)
  5. Topical outline (length limit: three pages), indicating the headings of sections and subsections, a brief discussion of the proposed content of each section, and key references for each section
  6. List of up to five of the authors’ papers related to the Global Perspective topic
  7. List of key previous articles on the subject in the past 5 years
  8. Justification for the need for a Global Perspective on the topic targeting the broader readership of ES&T Letters


An assigned editor will issue a decision on the proposal and if approved, the authors will be invited to submit a full Global Perspective for further consideration. If the full Global Perspective is favorably received by the assigned editor, the manuscript will then undergo peer review.


At submission of the full Global Perspective article, authors must provide a short synopsis statement (approximately 20 words), placed after the abstract, stating the environmental relevance and significance of their Global Perspective. Authors are also expected to provide an explanation in their cover letter why they believe the manuscript belongs in ES&T Letters and why their research will interest our readers with an emphasis on the novelty and environmental relevance of the contribution. All Global Perspective manuscripts must include a Key Messages section at the end summarizing in bullet form the main highlights and arguments of the manuscript.



A Highlight manuscript (length limit: 800-1000 word-equivalents + author affiliations + 5 references + 1 single-frame figure with 50-word caption OR a 350-word table) is a short manuscript, written in the style of a short news piece or brief opinion in a newspaper or magazine. It enables authors to rapidly publish information of a scientific nature and of pressing importance that impacts the environmental science and technology community in real time. Highlight articles should express urgent information based on scientific research in an environmental discipline, that should not be political, personal, or summary in nature. Highlight articles should not include new scientific data. Highlight articles are not peer reviewed but are reviewed internally by at least 2 members of the ES&T Letters editorial team. Corresponding authors of accepted articles will be requested to provide a short biography (up to 200 words) and headshot for inclusion at the end of the published article. A TOC graphic is not required for this manuscript type.



Readers are encouraged to provide scholarly comment on papers appearing in the research section (Letters, Reviews, Global Perspectives) via Correspondence/Rebuttal (length limit: 1,000 word-equivalents each including citations) manuscripts. Correspondence should be submitted within twelve months of the publication date of the original paper, with some flexibility in exceptional circumstances, and must raise substantive scientific or technical questions. Correspondence that consists mainly of opinion will not be considered. The author(s) of the original paper will be given an opportunity to prepare a response within one month of receiving the Correspondence. Correspondence on previously published Correspondence will not be considered, and personal invective will not be tolerated. Correspondence/Rebuttal may undergo peer review at the determination of the assigned editor. The correspondence and the rebuttal will be published consecutively in the same issue.

ACS Researcher Resources

While this document will provide basic information on how to prepare and submit the manuscript as well as other critical information about publishing, we also encourage authors to visit the ACS Researcher Resources for additional information on everything that is needed to prepare (and review) manuscripts for ACS journals and partner journals, such as

  • Mastering the Art of Scientific Publication, which shares editor tips about a variety of topics including making your paper scientifically effective, preparing excellent graphics, and writing cover letters.
  • Resources on how to prepare and submit a manuscript to ACS Paragon Plus, ACS Publications’ manuscript submission and peer review environment, including details on selecting the applicable Journal Publishing Agreement.
  • Sharing your research with the public through the ACS Publications open access program.
  • ACS Reviewer Lab, a free online course covering best practices for peer review and related ethical considerations. 
  • ACS Author Lab, a free online course that empowers authors to prepare and submit strong manuscripts, avoiding errors that could lead to delays in the publication process.
  • ACS Inclusivity Style Guide, a guide that helps researchers communicate in ways that recognize and respect diversity in all its forms.

Manuscript Preparation

Submit with Fast Format

All ACS journals and partner journals have simplified their formatting requirements in favor of a streamlined and standardized format for an initial manuscript submission. Read more about the requirements and the benefits these serves authors and reviewers here.


Manuscripts submitted for initial consideration must adhere to these standards:

  • Submissions must be complete with clearly identified standard sections used to report original research, free of annotations or highlights, and include all numbered and labeled components.
  • Figures, charts, tables, schemes, and equations should be embedded in the text at the point of relevance. Separate graphics can be supplied later at revision, if necessary.
  • When required by a journal's structure or length limitations, manuscript templates should be used.
  • References can be provided in any style, but they must be complete, including titles. For information about the required components of different reference types, please refer to the ACS Style Quick Guide.
  • Supporting Information must be submitted as a separate file(s).

Document Templates and Format

The use of manuscript templates is not required for ES&T Letters.


General information on the preparation of manuscripts may also be found in the ACS Guide to Scholarly Communication.

Acceptable Software, File Designations, and TeX/LaTeX

See the list of Acceptable Software and appropriate File Designations to be sure your file types are compatible with ACS Paragon Plus. Information for manuscripts generated from TeX/LaTeX is also available.

Cover Letter

A cover letter must accompany every manuscript submission. During the submission process, you may type it or paste it into the submission system, or you may attach it as a file.


The cover letter should include:

  • manuscript title
  • corresponding author’s name
  • corresponding author’s mailing address
  • corresponding author’s phone number, fax number, and e-mail address
  • comments on a) the manuscript’s significance and b) the need for urgent publication
  • list of related work submitted or published if relevant


Authors should note that a clear statement of the manuscript’s goals and significance can be very helpful to the Editors during the prescreening process. Authors are also expected to provide an explanation in their cover letter why they believe the manuscript belongs in ES&T Letters and why their research will interest our readers with an emphasis on the novelty and environmental relevance of the contribution.

Manuscript Text Components

Spell out all acronyms on first use in the abstract and in the body of the article. ES&T Letters does not allow footnotes, with the exception of an author information footnote on the title page and table detail/definition footnotes.


The various sections of the manuscript are described in detail below:

  • Title and Authorship
  • Abstract, Keywords, and Synopsis
  • Introduction
  • Materials and Methods
  • Results and Discussion
  • Abbreviations
  • Acknowledgment
  • References
  • Formula and Equations



Use a brief, specific, and informative title reflecting the content and emphasis of the paper. Keywords in titles assist in effective literature retrieval. If trade names are used, give generic names in parentheses.  Avoid abbreviations or acronyms and spell out in full.



List the full first name, middle initial(s), and last name of each author. Omit professional and official titles. An author’s affiliation should be based on where they were when the work was performed. When the present address of an author is different, include the new information in a footnote. In a paper with more than one author, the name of the corresponding author, to whom post-publication inquiries should be addressed, carries an asterisk (*). Provide an email address for the corresponding author.


Many Funders and Institutions require that institutional affiliations are identified for all authors listed in the work being submitted. ACS facilitates this requirement by collecting institution information during the manuscript submission process in ACS Paragon Plus (Step 3 in ACS Paragon Plus: Authors & Institutions).


Include as co-authors all those who have made a substantial contribution to the work.  All authors must have participated in the preparation of the manuscript and must have agreed to the version of the manuscript, supporting information, and all revisions submitted.  Addition or deletion of an author (s) after submission of the manuscript requires justification from the corresponding author and is subject to editorial approval.  Deceased persons who meet the criteria for inclusion as coauthors should be included, with an Author Information note indicating the date of death.


Abstract, Keywords, and Synopsis


All Letters, Reviews, and Global Perspectives must contain an abstract, not exceeding 200 words, which should state briefly the purpose of the research, methods or procedures, significant new results, and implications. Define any abbreviations or acronyms used in the abstract. Do not include reference numbers in the abstract.



Letters, Reviews, and Global Perspectives must be accompanied by 5–8 keywords. Authors are encouraged to include keywords that do not appear in the title. Indicate the keywords in the cover letter as well as in the manuscript file.



Letters, Reviews, and Global Perspectives should include a synopsis. A synopsis is a brief and succinct statement (~20 words) of the environmental implications and impact of your research work to the environmental research community. The synopsis should be a complete sentence. The synopsis is NOT a description of the TOC graphic.



The introduction should clearly and concisely explain the motivation for the work, its importance and originality, where it fits in the development of the field and why it should be of interest to ES&T Letters readers. Discuss relationships of the study to previously published work, but do not reiterate or provide a complete literature survey.  If a recent article has summarized work on the subject, cite that article only, and not the sources it cites.   Current findings should not be included or summarized in this section.  Introduction sections are typically around 500 words in length.


Materials and Methods

In this section, describe pertinent and critical factors involved in the experimental work but avoid excessive description. In many cases, details not essential for understanding the paper can be placed in Supporting Information (SI). However, placing all the experimental methods, or critical aspects of the methods, in the Supporting Information is not permitted. Specific experimental methods should be sufficiently detailed for others to repeat the experiments unequivocally. List and describe preparation of special reagents only. List devices of a specialized nature or instruments that may vary in performance or affect the quality of the data obtained (e.g., spectroscopic resolution), including the vendor. If the procedures are already published, provide citations to previous publications, and expand only on differences in the current work. Authors must emphasize any unexpected, new, and/or significant hazards or risks associated with the reported work and this safety information must be included in the Materials and Methods section. 


Results and Discussion

Here you can discuss your findings, postulate explanations for the data, elucidate models and compare your results with those of others.  Be complete but concise.  Avoid irrelevant comparisons or contrasts, any speculation unsupported by the data presented and verbose discussion. 


Results and discussion may be combined or separated into separate sections. Do not include a Conclusions or Summary section. Include major conclusions in the body of the Results and Discussion sections.



Specialized abbreviations may be used provided they are placed in parentheses after the word(s) at first point of use.  Do not include a separate Abbreviations list. Use SI units and consult the ACS Guide to Scholarly Communication for lists of SI units and preferred forms of commonly used abbreviations.



Include only essential credits to acknowledge financial or professional assistance to the conduct of research.  Sources of financial support must be acknowledged.  Omit academic and social titles.



All article types in ES&T Letters use the same reference style. Authors are encouraged to cite peer-reviewed works and books. Any references in publications that would be difficult for most reviewers to obtain or are unpublished should be uploaded into the ES&T Letters ACS Paragon Plus submission site as Information for ‘Review Only’.


References should be numbered in order of appearance in the text, and the corresponding numbers placed at the appropriate locations in the text as superscripted numerals without parenthesis. 


For work published online but not yet in an issue (ASAP) and work submitted for publication (e.g., submitted; in press), the digital object identifier (DOI) of the paper should be furnished in addition to the standard bibliographic information. DOI is an accepted form of citation before and after the article appears in an issue. The title of a journal article should be in sentence format (first letter capitalized, with the remaining title in lower case).


In the Web edition of the Journal, references will be linked to various electronic sources (e.g., the corresponding abstract from Chemical Abstracts Service, full text from other American Chemical Society journals, etc.); therefore, the accuracy of the references is critical. Authors are responsible for the accuracy of the references.


Formulae and Equations

Chemical formulas should be embedded in the text at the point of relevance and should correspond to the ACS Guide to Scholarly Communication. Chemical equations should be balanced and numbered consecutively along with mathematical equations. Mathematical arguments should be as brief as possible.


Supporting Information

This information is provided to the reviewers during the peer-review process (for Review Only) and is available to readers of the published work (for Publication). Supporting Information must be submitted at the same time as the manuscript. See the list of Acceptable Software by File Designation and confirm that your Supporting Information is viewable.


If the manuscript is accompanied by any supporting information files for publication, these files will be made available free of charge to readers. A brief, nonsentence description of the actual contents of each file, including the file type extension, is required. This description should be labeled Supporting Information and should appear before the Acknowledgement and Reference sections.  Examples of sufficient and insufficient descriptions are as follows:


Examples of sufficient descriptions: “Supporting Information: 1H NMR spectra for all compounds (PDF)” or “Additional experimental details, materials, and methods, including photographs of experimental setup (DOC)”.


Examples of insufficient descriptions: “Supporting Information: Figures S1-S3” or “Additional figures as mentioned in the text”.


When including supporting information for review only, include copies of references that are unpublished or in-press. These files are available only to editors and reviewers.

Research Data Policy

All ACS journals strongly encourage authors to make the research data underlying their articles publicly available at the time of publication.

Research data is defined as materials and information used in the experiments that enable the validation of the conclusions drawn in the article, including primary data produced by the authors for the study being reported, secondary data reused or analyzed by the authors for the study, and any other materials necessary to reproduce or replicate the results.

The ACS Research Data Policy provides additional information on Data Availability Statements, Data Citation, and Data Repositories.

Data Requirements


Use abbreviations and acronyms sparingly, and all usage should be defined at the first occurrence in the text. Whenever possible, use systematic nomenclature as recommended by IUPAC and IUBMB for chemical compounds and biomolecules, and SI units. The ACS and IUPAC websites have links to nomenclature recommendations. Usually, the chemical name or composition should be given in parentheses or in a reference at the first occurrence of such a name. Names of organisms should comply with genetic conventions, with genus and species names written in italics and spelled out in full on first appearance. Trademark names should be defined at the point of first use and registered trademark names should be capitalized whenever used. Registration marks are not required to ensure legal protection for the trademark. Trade and trivial names should not be capitalized.


Data Presentation

Data should be presented in a way that makes interpretation clear to the reader.

For more information on data presentation, see:

  1. Quantifying the Interactions between Biomolecules: Guidelines for Assay Design and Data Analysis
  2. Beyond Bar and Line Graphs: Time for a New Data Presentation Paradigm
  3. Reporting standards and availability of data, materials, code and protocols.
  4. MIQE guidelines for ddPCR and QPCR by Bustin et. al. 2009 and Hugget et. al. 2020; EMMI guidelines by Borchardt et al. 2021
  5. Best practice for 16S Microbiome studies


Biological Assays

Exposure protocols and methods must be referenced or described in sufficient detail to permit the experiments to be repeated by other investigators. This includes for example information on the preparation of the test materials, medium components, and duration of exposure. In addition, the applied dose or dose range should be given in a meaningful unit and the relevance of the applied dose should be substantiated. Doses and concentrations should be expressed as molar quantities (e.g., μmol/kg, mM, etc.), particularly when comparisons of potencies are made on compounds having large differences in molecular weights. The routes of administration of test compounds and vehicles should be indicated. Benchmarks should be included in form of appropriate positive or negative control substances or reference materials. Especially for studies on nanomaterials, assays should be checked for interference induced by nanomaterials, e.g., optical or chemical interference, masking of the analyte or other interference mechanisms by inclusion of appropriate controls. Also, for studies on nanomaterials, sterilization procedures and specification of dilution steps as well as the order of addition should be provided, and as far as possible, various measuring units related to dose (e.g., surface area, mass, particle number per surface area, volume, cell number) should be given to increase comparability with other studies. Data may be presented as numerical expressions or in graphical form. Statistical limits (statistical significance) for the biological data are usually required. If statistical limits cannot be provided, the number of determinations and some indication of the variability and reliability of the results should be given. References to statistical methods of calculation should be included.


Use of Human Subjects or Animals in Research

For information about carrying out and reporting on Human and Animal Studies, please refer to the Biological Data section of the ACS Research Data Guidelines.


Database Deposition

Advancing scientific discoveries can be enhanced when data and materials are made available and readily exchanged. ES&T Letters requires for all published articles that authors make materials, data, and protocols available to readers through deposition in a public database. A statement must appear in the submitted manuscript confirming submission of the data and indicating the data bank and any pertinent accession codes/ID.


To identify the repository that meets your particular needs, you may find FAIR Sharing Databases, Registry of Research Data Repositories, and Repository Finder helpful.  Authors may also want to further investigate unstructured and/or large data repositories, such as Dryad Digital Repository, figshare, Open Science Framework, and Zenodo, or institutional repositories for depositing data. If there is no appropriate repository available, general publicly available repositories should be used.


In addition, ACS Publications’ figshare houses all Supporting Information within the HTML presentation of the paper and at acs.figshare.com. Authors also agree to make available to interested academic researchers for their own use any materials reported in the manuscript that are not otherwise obtainable. Any restrictions to the availability of materials or information must be stated at the time of submission. The ACS Math Style Sheet and NMR Guidelines are available on ACS Researcher Resources.


Sequence Data

DNA and RNA sequence data can be submitted to suitable public repositories such as GenBank, European Nucleotide Archive (ENA), the DNA Data Bank of Japan (DDBJ), dbSNP, dbVar, Database of Genomic Variants archive (DGVa), MGnify, miRBase, NCBI Sequence Read Archive (SRA), and NCBI Trace Archives. Protein sequence data should be deposited with the Protein Identification Recourse at Georgetown University Medical Center, Washington, the European Bioinformatics Institute (EBI), the Swiss Institute of Bioinformatics, or UniProt.


Omics Data

Manuscripts that present microarray data should follow the MIAME (Minimum Information About a Microarray Experiment) guidelines. Data should be submitted to suitable public repositories such as ArrayExpress, Database of Interacting Proteins (DIP), dbGaP, Genomic Expression Archive (GEA),  Gene Expression Omnibus (GEO), IntAct Molecular Interaction Database, Global Natural Products Social Molecular Networking (GNPS), MassIVE, MetaboLights, Proteomics Identifications (PRIDE) Archive, and ProteomeXchange.


For sequence data and microarray data, the relevant accession numbers should be available at the time that the revision is submitted and should be listed at the end of the Materials and Methods section in the revised version of the manuscript.


Proteomics Data

Proteomic experiments must meet the standards established by the Journal of Proteome Research. More information is available in the Publication Guidelines for the Analysis and Documentation of Peptide and Protein Identifications. Protein sequences should be handled in the same way as described above, and accession number and database source should be included.


Computer Codes

When computer codes are developed or used and are an essential part of a manuscript, sufficient detail must be given, either within the paper or in the SI. Types of languages that are used in the computer codes, compiler/interpreter, and operating system with a specific version must be provided or properly cited. Upon request, after appropriate material transfer agreements to restrict the use of the materials so as to protect the legitimate interests of the authors, codes and input data must be made available for others to validate the calculations. Regardless of whether the source code is open or closed source, it must be properly cited in the References.


Computational Chemistry Calculations

When computational chemistry calculations are performed, input data— including force field parameters, equations defining the model (or references to where such material is available in the open literature), methods and approaches, and basis sets—must be given either within the paper or in the SI. If the software used for calculations is generally available, it must be properly cited in the References. References to the methods upon which the software is based must also be provided.



When requested, the authors should also make a reasonable effort to provide samples of unusual materials unavailable elsewhere, including, but not limited to, clones, microorganism strains, antibodies, computer codes, etc., to other researchers, with appropriate material transfer agreements to restrict the field of use of the materials so as to protect the legitimate interests of the authors. Any restrictions to the availability of materials or information must be stated at the time of submission.

Language and Editing Services

A well-written paper helps share your results most clearly. ACS Publications’ English Editing Service is designed to help scientists communicate their research effectively. Our subject-matter expert editors will edit your manuscript for grammar, spelling, and other language errors so your ideas are presented at their best.

Preparing Graphics

The quality of illustrations in ACS journals and partner journals depends on the quality of the original files provided by the authors. Figures are not modified or enhanced by journal production staff. All graphics must be prepared and submitted in digital format.


Graphics should be inserted into the main body whenever possible. Please see Appendix 2 for additional information.


Any graphic (figure chart, scheme, or equation) that has appeared in an earlier publication should include a credit line citing the original source. Authors are responsible for obtaining written permission to re-use this material.

Figure and Illustration Services

The impact of your research is not limited to what you can express with words. Tables and figures such as graphs, photographs, illustrations, diagrams, and other visuals can play a significant role in effectively communicating your findings. Our Artwork Editing and Graphical Abstract services generate publication-ready figures and Table of Contents (TOC) graphics that conform to your chosen journal’s specifications. For figures, this includes changes to file type, resolution, color space, font, scale, line weights, and layout (to improve readability and professional appearance). For TOC graphics, our illustrators can work with a rough sketch or concept or help extract the key findings of your manuscript directly for use as a visual summary of your paper.

Preparing for Submission

Manuscripts, graphics, supporting information, and required forms, as well as manuscript revisions, must all be submitted in digital format through ACS Paragon Plus, which requires an ACS ID to log in. Registering for an ACS ID is fast, free, and does not require an ACS membership. Please refer to Appendix 1 for additional information on preparing your submission

Prior Publication Policy

ES&T Letters considers only original work for publication that has not been previously published and is not under consideration for publication elsewhere. Related work under consideration for publication in any medium must be cited in the manuscript and the Editor-in-Chief informed at the time of submission. In addition, an author must inform the Editor-in-Chief of prior dissemination of the content in print or electronic formats in the cover letter. Posting of pre-prints to a pre-print server such as ChemRxiv, bioRXiv, arXiv, or applicable repository for their discipline before the manuscript is accepted for publication is considered acceptable but requires citing of the pre-print. Authors may revise the preprint version of their manuscript up until a final acceptance decision has been issued.  Please note the use of a pre-print server in the cover letter and provide a link to the preprint, and as appropriate, state how the manuscript has been adjusted/updated between deposition and submission.  All other prior/redundant publication is forbidden. Failure to alert ES&T Letters in your cover letter to any prior publication of your submission may be viewed as an ethical violation. Upon publication in ES&T Letters, authors are advised to add a link from the pre-print to the published paper via the Digital Object Identified (DOI) that is assigned to the published article. Some preprint servers, including ChemRxiv and bioRXiv, include this link for authors automatically after publication.



Authors submitting material that has been used in their thesis/dissertation must contact the Editor-in-Chief for approval. Authors will be asked to confirm that they alone hold the copyright to the work and to read and comply with the ACS dissertation policy and the conditions and procedures laid out in the ACS Journal Publishing Agreement (JPA). Authors will also need to make arrangements with their degree-granting institution (and any repositories to which their thesis/dissertation has been or will be posted) to either delay posting of the thesis/dissertation or remove the material from the Internet until the final paper is published by ES&T Letters (i.e., the work is considered under embargo). Finally, they will need to properly cite the ES&T Letters article in any versions of the thesis/dissertation made publicly available after the embargo period.


Authors wishing to include published ES&T Letters material in their thesis/dissertation should follow the guidelines of the ACS dissertation policy. They must contact the Editor-in-Chief for permission, and properly cite and link to the published ES&T Letters article.


Permission requests for all ACS Journal materials are handled through the RightsLink service. Please see the RightsLink instructions for complete details: https://pubs.acs.org/page/copyright/rightslink.html



Proceedings of conferences and symposia

Authors cannot publish presentations in proceedings (paper or electronic) that are copyrighted (except by ACS) and then submit them to ES&T Letters due to copyright concerns. If the proceedings are not copyrighted, publishing a short abstract without figures or tables is permissible. It is the responsibility of authors to notify ES&T Letters of any abstracts that have been published in any form.



ES&T Letters will consider for publication a paper or presentation that has been posted on a website available to the general public, provided that the site is the personal site of the author and is not connected to a commercial site. Authors must notify the journal at the time of submission if the material has been available on the Internet or equivalent electronic media and must remove the material from the site at the time of submission. If the website is a commercial site not owned by ACS, the authors are advised that consideration of the paper may be endangered. When the paper is published, authors may provide an electronic link from that site to the ES&T Letters homepage.



Authors must confirm that they alone hold the copyright to the report. If a government or funding organization requires posting of a related report, please contact the Editor-in-Chief and provide specific details.

Editorial Policies

Quality Expectations

Clearly articulating the importance of your research and the quality of presentation of your manuscript will have an important impact on the ease with which it can undergo peer review and the impression it gives to reviewers of its overall quality. If your writing is rambling, fails to establish the purpose of the research, provides an incoherent discussion, puzzling figures, or inappropriate scales on graph axes, the technical merits of your research will be less easy to recognize. Please articulate clearly the purpose of your work, write concisely and with clarity, and provide well thought-out and clearly presented figures and tables with appropriate considerations of the magnitude of error. This will significantly increase the likelihood that we will publish your research. ES&T Letters is aligned with ES&T regarding article quality submission standards (https://pubs.acs.org/doi/pdf/10.1021/acs.est.0c05784).


Length Limits

The length limits for each article type are listed in the Article Types section. Article length can be determined by counting all text, excluding title page, references, and figure/table captions. Next, add 200 words for each small figure, scheme, or table that takes up part of a page. Large multipart figures, extensive tables, detailed maps, or chemical pathways taking up a page or more should be counted as 600 words. At the discretion of the assigned editor, some figures or tables may be counted as more than 600 words.


Manuscripts that exceed the length limit will be un-submitted (returned to the Draft section in ACS Paragon Plus) with a request to shorten, or they may be immediately rejected. To reduce length, make the Introduction and Discussion sections more concise. In addition, make appropriate use of Supporting Information, which is readily available to all readers of the manuscripts on the ES&T Letters website.


Authors who believe that exceeding the length limit is essential must include a compelling argument in their cover letters. Ultimately, however, the decision about whether a manuscript that exceeds the recommended length is appropriate for review is made by the assigned editor.


Peer Review

All manuscripts submitted are reviewed and handled by the Editor-in-Chief and assigned to one of the Associate Editors. The Editor-in-Chief and Associate Editors evaluate the content and format of the paper. A significant fraction of manuscripts submitted to ES&T Letters are declined after review by an editor and are not sent for external review. Common reasons for declining manuscripts at this initial stage include insufficient urgency, novelty, lack of sufficient environmental relevance, failure to place the rationale for the study or the results in the context of existing literature, insufficient quality of the data, or problems with the manuscript presentation (length limits, inadequate English, figure quality). 


Manuscripts that meet editorial expectations are sent for external review to experts in the field. Associate editors select reviewers, monitor the progress of the review process, evaluate the comments of reviewers, and forward them to the authors for their response, communicating ultimate acceptance or rejection to the corresponding author and carrying out a final check of accepted manuscripts.


Peer review is used to ensure the highest possible quality in published manuscripts. Scientists with expertise in the subject matter are invited to evaluate the submission for its originality, validity, significance and impact on the field and suitability to the ES&T Letters. Typically, three reviewers are selected per paper on the basis of the subject matter, available expertise and the Editor’s knowledge of the subject area. Authors must also submit the names and addresses (including email addresses) of at least 4 potential reviewers who do not have conflicts of interest with the authors or manuscript content. Whenever possible, suggest academic email addresses rather than personal email addresses. However, the Editors are under no obligation to use specific individuals. Anonymous copies of the reviews and the Editor’s decision regarding the acceptability of the manuscript are sent to the corresponding author.  If the reviewers’ evaluations of the manuscript disagree, of if reviewer’s and Editor’s comments are not satisfactorily addressed by the authors, the Editor may reject the manuscript or select additional reviewers to further assist in reaching a final decision on the manuscript.


The editors may exercise their prerogative to decline a manuscript after editorial review if that paper is judged to outside the scope of ES&T Letters, is lacking in urgency, novelty, significance, or impact, is poorly written or formatted, or is fragmentary and marginally incremental in its contribution.


Submitting Revised Manuscripts and Response to Reviewers

Following the peer review of your manuscript, the corresponding author may be requested to perform a revision of the manuscript in order to fully satisfy all peer review comments.  If you are submitting a revised manuscript (or an authorized resubmission of a manuscript that was already peer reviewed), you must submit point-by-point responses to each of the comments of the reviewers. We recommend that you copy the reviewer’s comment into the text immediately prior to your response. You should also upload, as ‘Information for Review Only’, a version of the manuscript with changes highlighted to allow the editor to easily discern the revisions that have been made.


Resubmission of Previously Declined Manuscripts to ES&T Letters

If your manuscript is declined by ES&T Letters, read the decision letter carefully. Manuscripts are often declined because the editor determines that the subject matter is not appropriate for ES&T Letters or that the urgency, novelty, or significance of the manuscript is insufficient.


If you wish to submit a revised version of a declined manuscript to ES&T Letters, you must first contact the associate editor who handled your original submission to request permission to resubmit. If you receive permission to resubmit, indicate in your cover letter that it is an authorized revision of a previously submitted manuscript, provide the original manuscript number, and state how the manuscript has changed. If the manuscript was reviewed, submit a detailed, point-by-point list of your responses to each of the comments of the reviewers or provide convincing reasons for declining to do so. The manuscript should be submitted online (see the Manuscript Submission section of this Guide, below), where it will receive a new manuscript number. During the submission process, mark “Yes” when asked if the manuscript has been previously submitted “in whole or in part.” Manuscripts that editors judge to be resubmissions, in whole or in part, of previously submitted manuscripts that do not comply with these rules will not be considered for publication. Moreover, failure to alert ES&T Letters to a resubmission, even in part, is an ethical violation.


Appeal Process

If your manuscript is declined by ES&T Letters and the author believes an error has been made, you may appeal the decision directly to the editor who made it, providing a clear explanation for why you believe he or she should reconsider the decision. If the editor upholds the rejection, you may appeal the decision to the Editor-in-Chief (eic@estlett.acs.org). When outlining your appeal to the Editor-in-Chief, please include confirmation that you first asked the handling editor to reconsider the decision and then provide a clear explanation as to why you believe that the associate editor’s decision is unreasonable. The Editor-in-Chief’s decisions on appeals are final.


This same process should be used for appealing an editor’s denial of your request to resubmit a previously submitted manuscript.


Press Release and Request for an Embargo

If your institution plans to put out a press release if/when your paper is published, and this press release requires prior embargo (a hold in publication date) of the paper, please do the following: Once your paper is accepted, contact the managing editor (managing.editor@est.acs.org) and the Journal Production office and notify them of the intended press release. They will coordinate publication of the paper to coincide with the press release.

Providing Potential Reviewer Names

Please suggest 4 reviewers. Authors are encouraged to avoid suggesting reviewers from the authors’ institutions. Do not suggest reviewers who may have a real or perceived conflict of interest. Whenever possible, suggest academic email addresses rather than personal email addresses.

Manuscript Transfer

If your submission is declined for publication by this journal, the editors might deem your work to be better suited for another ACS Publications journal or partner journal and suggest that the authors consider transferring the submission. Manuscript Transfer simplifies and shortens the process of submitting to another ACS journal or partner journal, as all the coauthors, suggested reviewers, manuscript files, and responses to submission questions are copied by ACS Paragon Plus to the new draft submission. Authors are free to accept or decline the transfer offer.


Note that each journal is editorially independent. Transferring a manuscript is not a guarantee that the manuscript will be accepted, as the final publication decision will belong to the editor of the next journal.


Proofs via ACS Direct Correct

Correction of the galley proofs is the responsibility of the Corresponding Author. The Corresponding Author of an accepted manuscript will receive e-mail notification and complete instructions when page proofs are available for review via ACS Direct Correct. Extensive or important changes on page proofs, including changes to the title or list of authors, are subject to review by the editor.


It is the responsibility of the Corresponding Author to ensure that all authors listed on the manuscript agree with the changes made on the proofs. Galley proofs should be returned within 48 hours in order to ensure timely publication of the manuscript.

Publication Date and Patent Dates

Accepted manuscripts will be published on the ACS Publications Web site as soon as page proofs are corrected and all author concerns are resolved. The first date on which the document is published on the Web is considered the publication date.


Publication of manuscripts on the Web may occur weeks in advance of the cover date of the issue of publication. Authors should take this into account when planning their patent and intellectual property activities related to a document and should ensure that all patent information is available at the time of first publication, whether ASAP or issue publication.


All articles published ahead of print receive a unique Digital Object Identifier (DOI) number, which is used to cite the manuscript before and after the paper appears in an issue. Additionally, any supplemental information submitted along with the manuscript will automatically be assigned a DOI and hosted on Figshare to promote open data discoverability and use of your research outputs.

ASAP Publication

Manuscripts will be published on the “ASAP Articles” page on the web as soon as page proofs are corrected and all author concerns are resolved. ASAP publication usually occurs within a few working days of receipt of page proof corrections, which can be several weeks in advance of the cover date of the issue.

Post-Publication Policies

The American Chemical Society follows guidance from the Committee on Publication Ethics (COPE) when considering any ethical concerns regarding a published article, Retractions, and Expressions of Concern.

Additions and Corrections

Additions and Corrections may be requested by the author(s) or initiated by the Editor to address important issues or correct errors and omissions of consequence that arise after publication of an article. All Additions and Corrections are subject to approval by the Editor, and should bring new and directly relevant information and corrections that fix scientific facts. Minor corrections and additions will not be published. Readers who detect errors of consequence in the work of others should contact the corresponding author of that work.


Additions and Corrections must be submitted as new manuscripts via ACS Paragon Plus by the Corresponding Author for publication in the “Addition/Correction” section of the Journal. The corresponding author should obtain approval from all coauthors prior to submitting or provide evidence that such approval has been solicited. The manuscript should include the original article title and author list, citation including DOI, and details of the correction.


Articles may be retracted for scientific or ethical reasons and may be requested by the article author(s) or by the journal Editor(s), but are ultimately published at the discretion of the Editor. Articles that contain seriously flawed or erroneous data such that their findings and conclusions cannot be relied upon may be retracted in order to correct the scientific record. When an article is retracted, a notice of Retraction will be published containing information about the reason for the Retraction. The originally published article will remain online except in extraordinary circumstances (e.g. where deemed legally necessary, or if the availability of the published content poses public health risks).

Expressions of Concern

Expressions of Concern may be issued at the discretion of the Editor if:

  • there is inconclusive evidence of research or publication misconduct by the authors;
  • there is evidence that the findings are unreliable but the authors’ institution will not investigate the case;
  • an investigation into alleged misconduct related to the publication either has not been, or would not be, fair and impartial or conclusive;
  • an investigation is underway but a judgment will not be available for a considerable time.


Upon completion of any related investigation, and when a final determination is made about the outcome of the article, the Expression of Concern may be replaced with a Retraction notice or Correction.

Sharing Your Published Article

At ACS Publications, we know it is important for you to be able to share your peer reviewed, published work with colleagues in the global community of scientists. As sharing on sites known as scholarly collaboration networks (SCNs) is becoming increasingly prevalent in today’s scholarly research ecosystem, we would like to remind you of the many ways in which you, a valued ACS author, can share your published work.


Publishing open access makes it easy to share your work with friends, colleagues, and family members. In addition, ACS Publications makes it easy to share your newly published research with ACS Articles on Request (see below). Don’t forget to promote your research and related data on social media, at conferences, and through scholarly communication networks. Increase the impact of your research using the following resources: Altmetrics, Figshare, ACS Certified Deposit


When your article is published in an ACS journal or partner journal, corresponding authors are provided with a link that offers up to 50 free digital prints of the final published work. This link is valid for the first 12 months following online publication, and can be shared via email or an author’s website. After one year, the access restrictions to your article will be lifted, and you can share the Articles on Request URL on social media and other channels. To access all your Articles on Request links, log in to your ACS Researcher Resources account and visit the “My Published Manuscripts” page.


Article, journal, and commercial reprints are available to order.


We’ve developed ACS’ publishing and editorial policies in consultation with the research communities that we serve, including authors and librarians. Browse our policies below to learn more.

Ethical Guidelines

ACS editors have provided Ethical Guidelines for persons engaged in the publication of chemical research—specifically, for editors, authors, and reviewers. Each journal also has a specific policy on prior publication.

OFAC Compliance

As a U.S.-based non-profit organization, the American Chemical Society (ACS) is required to comply with U.S. sanctions laws and regulations administered by the U.S. Treasury Department’s Office of Foreign Assets Control (OFAC). While these laws and regulations permit U.S.-based publishers like ACS to engage in publishing-related activities with authors located in sanctioned regions in many cases, ACS may be prohibited under U.S. law from engaging in publishing-related activities in some cases, including, but not limited to, instances where an author or the institution with which an author is affiliated is located in a particular sanctioned region or has been designated by OFAC as a Specially Designated National (SDN) pursuant to certain U.S. sanctions programs. ACS reserves the right to refrain from engaging in any publishing-related activities that ACS determines in its sole discretion may be in violation of U.S. law.


Safety Considerations

Authors must emphasize any unexpected, new, and/or significant hazards or risks associated with the reported work. This information should be in the Experimental Section of a full article and included in the main text of a letter. Statement examples can be found in the Safety Statement Style Sheet and additional information on communicating safety information from the ACS Guide to Scholarly Communication is freely available here.

Conflict of Interest Disclosure

A statement describing any financial conflicts of interest or lack thereof is published in each ACS journal and partner journal article.


During the submission process, the Corresponding Author must provide a statement on behalf of all authors of the manuscript, describing all potential sources of bias, including affiliations, funding sources, and financial or management relationships, that may constitute conflicts of interest. If the manuscript is accepted, the statement will be published in the final article.


If the manuscript is accepted and no conflict of interest has been declared, the following statement will be published in the final article: “The authors declare no competing financial interest.”


In publishing only original research, ACS is committed to deterring plagiarism, including self-plagiarism. ACS Publications uses CrossCheck's iThenticate software to screen submitted manuscripts for similarity to published material. Note that your manuscript may be screened during the submission process.


Further information about plagiarism can be found in Part B of the Ethical Guidelines to Publication of Chemical Research. See also the press release regarding ACS' participation in the CrossCheck initiative.

Authorship, Author List, and Coauthor Notification

Authors are required to obtain the consent of all their coauthors prior to submitting a manuscript. The submitting author accepts the responsibility of notifying all coauthors that the manuscript is being submitted.


During manuscript submission, the submitting author must provide contact information (full name, email address, institutional affiliation, and mailing address) for all of the coauthors. Because all of the author names are automatically imported into the electronic Journal Publishing Agreement, the names must be entered into ACS Paragon Plus. (Note that coauthors are not required to register in ACS Paragon Plus.) Author affiliation should reflect where the work was completed, even if the author has since left that institution. Authors may include a note with a current address if their institution has changed since the work was completed.


To expedite the processing of your manuscript, please format your author and affiliation information according the guidelines in this link: https://pubsapp.acs.org/paragonplus/submission/author-address-information.pdf.


Criteria for authorship can be found in Part B of the Ethical Guidelines to Publication of Chemical Research. Artificial intelligence (AI) tools do not qualify for authorship. The use of AI tools for text or image generation should be disclosed in the manuscript within the Acknowledgment section with a description of when and how the tools were used. For more substantial use cases or descriptions of AI tool use, authors should provide full details within the Methods or other appropriate section of the manuscript.


If any change in authorship is necessary after a manuscript has been submitted, confirmation is required that all of the authors (including those being added or removed) have been notified and have agreed to the change. To provide this confirmation, authors are asked to complete and sign an authorship change form and provide the completed form to the appropriate editorial office.


Authors with a single name: If you, or any of your coauthors, have only one name, please follow these steps for proper submission to ACS Paragon Plus:

  1. First (Given) Name Field: Enter an asterisk (*) into the "First (Given) Name" field.
  2. Last (Family) Name Field: Enter your single name into the "Last (Family) Name" field.

If your paper is accepted, the asterisk (*) will be removed from the published version of the paper.



Patent Activities and Intellectual Property

Authors are responsible for ensuring that all patent activities and intellectual property issues are satisfactorily resolved prior to first publication (ASAP or in issue). Acceptance and publication will not be delayed for pending or unresolved issues of this nature.

Open Researcher and Contributor ID (ORCID)

Authors submitting manuscript revisions are required to provide their own personal, validated ORCID iD before completing the submission, if an ORCID iD is not already associated with their ACS Paragon Plus user profiles. This ID may be provided during original manuscript submission or when submitting the manuscript revision. All authors are strongly encouraged to register for an ORCID iD, a unique researcher identifier. The ORCID iD will be displayed in the published article for any author on a manuscript who has a validated ORCID iD associated with ACS when the manuscript is accepted.


ORCID iDs should not be typed into the manuscript. ACS publishes only those ORCID iDs that have been properly verified and linked before the manuscript is accepted. After your ORCID iD is linked, it will be displayed automatically in all subsequently accepted manuscripts for any/all ACS journals. We do not publish ORCID iDs provided during proof review or via other communications after a manuscript is accepted for publication.


With an ORCID iD, you can create a profile of your research activities to distinguish yourself from other researchers with similar names, and make it easier for your colleagues to find your publications. If you do not yet have an ORCID iD, or you wish to associate your existing ORCID iD with your ACS Paragon Plus account, you may do so by clicking on “Edit Your Profile” from your ACS Paragon Plus account homepage and following the ORCID-related links. Learn more at www.orcid.org.

To obtain forms and guidelines for completing the Journal Publishing Agreement or obtaining permissions from copyright owners, and to explore a Copyright Learning Module for chemists, click here.

Funder Reporting Requirement

Authors are required to report funding sources and grant/award numbers. Enter ALL sources of funding for ALL authors in BOTH the Funder Registry Tool in ACS Paragon Plus and in your manuscript to meet this requirement.

Open Access Compliance

ACS offers options by which authors can fulfill the requirements for open access and deposition into repositories for funded research. Visit our ACS Open Science site to see how to fulfill requirements for specific funders and to find out if you are eligible to publish under a Read + Publish agreement between ACS and your institution. You can also find out more about Open Access Compliance and ACS Open Science initiatives.

Diversity and Inclusion Statement

During manuscript submission, ACS journal authors have the option to submit a statement sharing information related to diversity and inclusion that is relevant for their paper. If supplying a diversity and inclusion statement, the corresponding author must provide this on behalf of all authors of the manuscript during the submission process. These statements include but are not limited to analysis of citation diversity and acknowledgment of indigenous land on which research was conducted. Statements expressing political beliefs are not permitted and may be removed by the journal office. All statements are subject to final review by the Editor.

  • Citation Diversity Statement:The citation diversity statement should appear in the Acknowledgements section of the manuscript. ACS recommends including the following: (1) the importance of citation diversity, (2) the proportion of citations by gender and race/ethnicity for the first and last authors, (3) the method used to determine those proportions and its limitations, and (4) steps taken to by the authors to improve citation diversity in the article. We recognize that one limitation of the current methods is that it cannot account for intersex, non-binary, and transgender people, or Indigenous and mixed-race authors. (Adapted from BMES/Springer Guidelines)
  • Land acknowledgment:The land acknowledgment statement should appear in the Acknowledgements section of the manuscript. The statement should link to the institutions’ formal land acknowledgments on which the research took place, if possible. Further guidance for creating these statements can be found here: https://nativegov.org/news/a-guide-to-indigenous-land-acknowledgment/.


Appendix 2: Preparing Graphics


Digital graphics pasted into manuscripts should have the following minimum resolutions:

  • Black and white line art, 1200 dpi
  • Grayscale art, 600 dpi
  • Color art, 300 dpi


Graphics must fit a one- or two-column format. Single-column graphics can be sized up to 240 points wide (3.33 in.) and double-column graphics must be sized between 300 and 504 points (4.167 in. and 7 in.). The maximum depth for all graphics is 660 points (9.167 in.) including the caption (allow 12 pts. For each line of caption text). Lettering should be no smaller than 4.5 points in the final published format. The text should be legible when the graphic is viewed full-size. Helvetica or Arial fonts work well for lettering. Lines should be no thinner than 0.5 point.


Color may be used to enhance the clarity of complex structures, figures, spectra, and schemes, etc., and color reproduction of graphics is provided at no additional cost to the author. Graphics intended to appear in black and white or grayscale should not be submitted in color.

Type of Graphics

Table of Contents (TOC)/Abstract Graphic

Consult the Guidelines for Table of Contents/Abstract Graphics for specifications.

Our team of subject-matter experts and graphical designers can also help generate a compelling TOC graphic to convey your key findings. Learn more about our Graphical Abstract service.


A caption giving the figure number and a brief description must be included below each figure. The caption should be understandable without reference to the text. It is preferable to place any key to symbols used in the artwork itself, not in the caption. Ensure that any symbols and abbreviations used in the text agree with those in the artwork.


Charts (groups of structures that do not show reactions) may have a brief caption describing their contents.


Each table must have a brief (one phrase or sentence) title that describes the contents. The title should be understandable without reference to the text. Details should be put in footnotes, not in the title. Tables should be used when the data cannot be presented clearly in the narrative, when many numbers must be presented, or when more meaningful inter-relationships can be conveyed by the tabular format. Tables should supplement, not duplicate, information presented in the text and figures. Tables should be simple and concise.


Each scheme (sequences of reactions) may have a brief caption describing its contents.

Chemical Structures

Chemical structures should be produced with the use of a drawing program such as ChemDraw.

Cover Art

ES&T Letters authors are encouraged to submit images to be considered for use on the journal’s front cover or Supplementary Covers at the time of the submission of their revised manuscript. If your article is accepted for publication, your artwork suggestion may also be selected for use on one of the journal’s covers. If your art is selected for front cover, ACS will send you information about how to request one complimentary 18” by 24” printed poster featuring your work. Images chosen for the front cover will be published at no cost to the author.


Cover image submissions should be eye-catching, imaginative and original. Unpublished images are encouraged. The cover image should not resemble a graphical abstract or data figure, but rather should be an artistic and scientifically accurate representation of the manuscript.


Image files should be submitted as TIF, JPG, PNG or EPS files with a resolution of at least 300 dpi for pixel-based images. Images should be 8.19 in × 10.00 in. (or 20.80 cm × 25.40 cm). Please note that the journal title will cover the top 3 in. (7.62 cm) of the image. Authors should submit the cover image along with a 5-10 word caption explaining the artwork, and a short, clear legend (less than 50 words) that will appear alongside the front cover explaining the image, as supplementary files to ACS Paragon Plus with their revised manuscript.


If you wish to be considered only for the front cover which is published at no cost to the authors, and not a paid supplementary cover, please respond NO accordingly to the Supplementary Cover Art question in ACS Paragon Plus. For more information on the Supplementary Covers program, please see this webpage. All art submitted for consideration for a supplementary cover will also be considered for a front cover.

Web Enhanced Objects (WEO) | Approved Graphics Programs

Web Enhanced Objects (WEO)

The Web editions of ACS journals allow readers to view multimedia attachments such as animations and movies that complement understanding of the research being reported.


WEOs should be uploaded in ACS Paragon Plus with ‘Web Enhanced Object’ selected as the file designation. Consult the list of compatible WEO formats.

Approved Graphics Programs and Websites with Compliant Copyright Licenses for Commercial Use

To comply with copyright rules, the following websites and graphics programs have copyright license wording that is acceptable to allow commercial use of their images and created graphics.  It remains the responsibility of the author to obtain or purchase the correct copyright license agreement from the recommended vendors listed below.

  • iStock (standard license)
  • Frontier Media (authors own copyright and allow CC-BY license)
  • Adobe (standard license)
  • TurboSquid (royalty free license)
  • Cinema4D (www.maxon.net)
  • Pexels
  • Pickit
  • Freeimages.com
  • Autodesk 3DS Max 2015 software
  • Photoshop
  • Inkscape
  • Dreamstime.com
  • ChemDraw
  • PyMOL
  • Microsoft ClipArt
  • Wordclouds.com
  • Piktochart
  • 123RF.com
  • Blender
  • Mapchart
  • Brusheezy
  • openclipart.org (CC-BY - allows commercial use)
  • Shutterstock (standard license)
  • eLife Science (creative commons license)
  • Megapixel (royalty free license)
  • Protein Database
  • Visual Molecular Dynamics (VMD)
  • gettyimages.com
  • Protter
  • Shade 3D
  • 3D Max
  • QGIS software (uses GNU General Public licenses)
  • "R" software (uses GNU General Public license)
  • SVG Map v 1.5
  • GIMP
  • Avogadro Software
  • 3D Sketchup Software
  • Solidworks
  • ArcGIS
  • Affinity Designer (v 1.7, Serif Europe Ltd.)
  • dreamgenerator.com
  • XCrySDen
  • National Gallery of Art/NGA Images. With the launch of NGA Images, the National Gallery of Art in Washington, DC implements an open access policy for digital images of works of art that the Gallery believes to be in the public domain. Images of these works are now available free of charge for any use, commercial or non-commercial. Users do not need to contact the Gallery for authorization to use these images as long as credit is given to the National Gallery of Art, Washington, DC. The images are available for download at the NGA Images website (images.nga.gov).